PROSTATE CANCER

A tip of the rough, 5-millimeter-long radioactive particles, through the rectal ultrasound (or CT and MRI) guidance, implanted within the prostate, issued by the use of particle radiation to kill prostate cancer cells, known as "prostate brachytherapy" method, Beijing Xiehe hospitals in China recently introduced the first set of equipment after the United States, used to treat prostate cancer a new method. According to European and American countries years of clinical research, this method is expected to become the most commonly used prostate cancer treatment, the most effective means.

I am suffering from prostate hyperplasia, recently accepted the transurethral resection of prostate. After resection of the prostate tissue, the pathological examination revealed cancerous lesions, it allows me great mental burden. Whether this will be the development of cancer, the treatment needs to be done further? — Hebei readers afternoon LI

A: The current benign prostate disease (mainly BPH) for the diagnosis, after resection of the prostate biopsy of the prostate cancer found that the accident, called sporadic cancer. This type of prostate cancer incidence rate of about 3% to 10%.

Treatment of prostate cancer patients with life expectancy and social relations, family and economic situation correspond to the current surgery and radiotherapy only hope to cure prostate cancer, but only a small number of patients suitable for both therapy. Many palliative therapy only, can ease symptoms, but the patient will not have an impact on survival. Therefore, treatment should be integrated in all aspects, the development of rational treatment programs. Current clinical treatment methods used as follows:

1. Endocrine therapy of prostate cancer with typical hormone-dependent, in clinical endocrine treatment of prostate lesions and can significantly ease symptoms, but with no obvious impact on survival.

Clinical treatment for prostate cancer chemotherapy more, into a single agent chemotherapy and two forms of chemotherapy, doctors are required under the guidance of the selection conditions. Medication For example:

■ single agent chemotherapy
(1) 5 - fluorouracil (5-FU): daily 15 mg per kg of body weight, on the 10th for a course of treatment, followed by injection every 2,500 milligrams a week by the internal iliac artery injection.

(2) brilliant Adriamycin: hematogenous metastasis of prostate cancer have a 60% efficiency. Daily 0.025 mg per kg body weight per day or 2-6 mg intravenous injection, the 10th for a course of treatment.

Prostate cancer is common urological cancer, early often asymptomatic, most of the patients when treatment is already advanced. Some patients because of distant metastases, traced search for the source of prostate cancer at diagnosis. The treatment of prostate cancer is still a radical resection of the prostate, endocrine therapy and radiotherapy. For the treatment of advanced prostate cancer, hormonal therapy and that radiation therapy is the most effective means. Common methods for testicular castration operation, anti - androgen drugs such as flutamide, a KANG Shi.

Endocrine therapy for the treatment of early prostate cancer satisfied with the results, but with the passage of time, transformed into a prostate cancer - androgen-independent cells, a PSA rise, affecting endocrine therapy. Radiation therapy is the treatment of advanced prostate cancer effective method, interference radiation on DNA synthesis, can effectively kill tumor cells, reduce infiltration around the tumor and lower. Apart from the radiation therapy, radiation particles implant brachytherapy, in recent years the rapid development of new technologies, the effect of high-low complication of normal tissues to radiation damage to the minimum extent. Particulate radiation brachytherapy implant can be used in early and advanced prostate cancer.

Prostate cancer brachytherapy method is the basic specifications of a certain number of sources directly inserted into the prostate, prostate cancer cells to high doses. In order to be satisfied with the treatment site dose, must formulate specific preoperative treatment planning system, according to sources around the dose distribution of the rules with a certain amount of these radioactive sources. Prostate cancer radiation therapy using CT, MRI and other imaging computer 3D reconstruction of the pool cloth reasonable and reliable. Through tablets tablets source of activity and spacing adjustment to the target dose uniformity, the target dose of a sudden drop, which will help protect normal tissue. Using the short half-life of radioactive nuclides, to kill or inhibit the proliferation of fast tumor cells more favorable. Treatment is simple, injury, protective security, and other benefits. Current prostate brachytherapy treatment of multiple choice I Pa 103 or 125.

Two Zhejiang Medical Center urology in the province in the first brachytherapy treatment of prostate cancer, nearly five years for a total of 100 cases of prostate cancer, including many other cases of failure, through our years of observation, patients with most cases PSA values decreased significantly, and prostate cancer mass was soft, small change, no serious complications in patients with prolonged survival time and improve the quality of life. Through clinical analysis, we believe that brachytherapy treatment of brachytherapy treatment of prostate cancer is an effective alternative method.

Many patients may be given the long-term local control, or even cured. But the administration can be a lot of factors such as tumor grade, stage and PSA levels before treatment, even for a partial clinical prostate cancer patients. Tumor-level low, confined to the organ survival rate of patients with prostate and substance cancer is the same age group. some localized prostate cancer in elderly patients, especially well-differentiated, may need treatment (for example, be observed), the risk of death due to other causes than of prostate cancer. but most patients choose radical prostatectomy or radiotherapy. For more age Light patients, radical prostatectomy may be the best, be a long life expectancy, the risk of urinary incontinence in the smallest (about 2%). about 50% of patients can maintain erectile function (eg, at least you can retain a nerve plexus). radiotherapy can have similar results, and special other treatment in patients with low levels of PSA. the standard radiation therapy in general to seven weeks with 70Gy (7000rad) exposure. 3D technology to safely increase the exposure amounted to CAT (8000rad), preliminary data show that higher local control rate. interstitial radiation (radioactive seed implantation) it had the same effect yet to be assessed.