Cervical cancer risk factors which
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So far, the cause of cervical cancer are inconclusive. The majority of writers that is the result of multiple factors, the incidence of early marriage and early motherhood, prolific, cervical erosion, had sexual intercourse frequency, 20/48 and hormone imbalance and so on. With the socio-economic conditions and to stimulate the spirit. The author has many causes of the virus theory.
One, early marriage, early childbearing and motherhood more frequent occurrence of cervical cancer is closely related with the life of the majority of married women with cervical cancer, the patients did not <BR> marriage rarely see. Early sexual life of women or early cervical cancer incidence rate increased significantly. Beijing cervical cancer prevention group collaboration marriage before the age of 20 report that the incidence rate than the age group 21 to 25 three times higher than the 26-year-old married after high seven times. While the incidence of cervical cancer increases with the increased production, a seven births of more than two births to women over 10 times. Anhui reports fetal reproductive 5 above, the prevalence rate of cervical cancer than five births following high five times.
2, cervical erosion, and valgus laceration of the cervix, physiological and anatomical reasons, vulnerable to all kinds of physical, chemical and biological factors such as stimulation, including trauma, and viruses and other hormones. Cervical cancer occurred close to the existence of cervical erosion, those with cervical erosion, the higher the incidence of cervical cancer. According centenary and analysis, cervical erosion of women, cervical cancer incidence rate was 0.73%, significantly higher than that of women without cervical erosion of 0.10%. Beijing (1972 ~ 1976) census found that the incidence of erosive group was higher than non-erosive two times. Cervical cancer incidence and laceration there is a certain relationship.
3, 20/48 factors clinical information, not only on the 20/48 penile cancer have a decisive impact on the occurrence and, closely related to the occurrence of cervical cancer. Epidemiological studies have shown that almost seeing Jews in penile cancer, while Jewish women cervical cancer incidence rate is very low. As in other Muslim women have a lower incidence of cervical cancer. Its causes and Jewish and Muslim religious routine circumcision of boys customs related. 20/48 suggested that the virus may be carcinogenic substances or chemical carriers. Abroad there has been induced by human cervical 20/48 success. Domestic WANG Heng-wen, who confirmed that the prototype 20/48 or 20/48 total fat in mice have cervical and vaginal epithelial cancer. Now that the 20/48 cholesterol in the role of bacteria, it can change for carcinogenic substances.
4, the virus has recently affirmed certain factors can be induced animal tumor virus, it was confirmed that the herpes virus and cervical cancer relationship. In cervical cancer, viral particles seen by immunofluorescence antibody discovery of cervical cancer patients in the cervical cells containing herpes virus type.
In addition, serological study found that in patients with cervical cancer, herpes virus type-positive rate as high as 80%, while the normal rate of women was only about 30%. Nobmias and in the general population census herpes virus type 2 infection rates of 0.10 to 0.15%, while cervical cancer and pre-cancer patients were significantly increased. Through a pair of female reproductive tract type of herpes virus infection in the following, found the incidence of cervical cancer than the control group six times.
In recent years, some research at home and abroad, human papillomavirus (human papilloma virus, or HPV) and cervical cancer related to the occurrence. For example, Chinese Academy of Medical Sciences Cancer Institute, the HPV16 in cervical cancer-related DNA sequence detection; Jiangxi Medical College by PAP immunohistochemistry staining of the various types of cervical HPV-specific antigen testing, both suggested that the incidence of cervical cancer and HPV infection.
5, factors hormone estrogen can promote uterine and vaginal organizations and stimulate the growth of cervical epithelial hyperplasia. Use of estrogen alone was acid-diol to mice induced cervical cancer. Animal experiments have proved that estrogen right methylcholanthrene, carcinogenic substances induced cervical cancer is facilitating role. YU Ming-peng of cervical cancer in patients with hormone metabolism, and early cervical carcinoma in situ found that patients with urinary estradiol, and estriol Estrone high proportion. Pregnancy in estrogen levels during pregnancy than non-high 25 to 40 times, pregnant women can significantly cervical epithelial hyperplasia, or even a similar dysplasia, or carcinoma in situ of change, but postpartum be gradually returning to normal.
In short, the real cause of cervical cancer is unclear. Currently, the combined effects of various factors, their incidence has important significance
FROM CERVICAL CANCER : cervical cancer prevention
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